Three modes. Hundreds of clinical applications. One learning curve worth climbing.
The Three Workflow Modes
Every clinical AI task fits one of three patterns. Matching the task to the right mode determines quality of output.
A fresh conversation, no setup, no memory. Like texting a consultant who knows everything but nothing about you specifically.
Best for: DDx brainstorm · terminology · quick literature check · drafting a patient message · explaining a lab value
Upload files — protocols, guidelines, spreadsheets, drafts — and Claude works within that context. The more you give it, the better it performs.
Best for: Reviewing a guideline PDF · editing a manuscript · analyzing a dataset · comparing two protocols
A persistent workspace that remembers your instructions, files, and style across every session. Set it up once; it works for you indefinitely.
Best for: AJOG reviewer workflows · research programs · teaching material libraries · ongoing writing projects
What Each Mode Cannot Do
| Mode | Does NOT have | Workaround |
|---|---|---|
| Focused Session | Memory of past sessions, your files, your style | Paste relevant context at the top of each message |
| Workspace | Persistence across sessions (files reset) | Re-upload files each session or use Projects |
| Projects | Real-time web access (unless Search is enabled) | Enable Web Search tool, or paste current data in |
Claude-Specific Features Worth Knowing
Most clinicians use 20% of what Claude can do. These features change the ceiling.
Claude reasons through complex problems step by step before answering. Surfaces contradictions, weights evidence, flags uncertainty. Turn it on for diagnostic reasoning, guideline critique, or multi-variable decisions.
Claude.ai ProClaude searches the current web in real time. Use for recent trial results, drug updates, FDA alerts, or anything post-2024. Toggle it on — it's off by default in most conversations.
Available freeUpload PDFs, Word docs, spreadsheets, images. Claude reads them in full. Upload a guideline and ask it to compare against your protocol. Upload a dataset and ask for statistical analysis.
Available freeClaude generates a separate panel for documents, code, HTML tools, spreadsheets, and presentations — not just chat text. Ask it to build a patient handout, a risk calculator, or a slide deck and it appears in a live preview.
Available freeA persistent workspace. Upload your files, write instructions, and Claude carries everything across every session. Ideal for residency teaching libraries, manuscript projects, or recurring review workflows.
Claude.ai ProClaude remembers facts about you across separate conversations — your specialty, your writing style, your recurring collaborators. It builds a profile over time. You can view and edit it anytime.
Claude.ai ProMulti-step research that searches dozens of sources, synthesizes, and produces a formatted report with citations. Takes 5–30 minutes. Ideal for systematic literature reviews, guideline backgrounds, or grant prep.
Claude.ai ProA separate command-line tool that writes, runs, and debugs code. Useful for data analysis pipelines, CDC natality database queries, statistical scripts, or building custom clinical tools. Separate from the chat interface.
CLI ToolPlan Levels: What You Get at Each Tier
Claude is available at four levels. The free tier is a genuine starting point. Pro is where clinical workflows become sustainable. Team and Enterprise add organizational controls.
| Feature | Free | Pro ~$20/mo | Team ~$30/user | Enterprise Custom |
|---|---|---|---|---|
| Conversation access | ✓ Limited daily | ✓ Higher limits | ✓ Higher limits | ✓ Custom limits |
| Document upload | ✓ | ✓ | ✓ | ✓ |
| Web Search | ✓ | ✓ | ✓ | ✓ |
| Artifacts | ✓ | ✓ | ✓ | ✓ |
| Projects | — | ✓ | ✓ | ✓ |
| Memory | — | ✓ | ✓ | ✓ |
| Extended Thinking | — | ✓ | ✓ | ✓ |
| Deep Research | — | ✓ | ✓ | ✓ |
| Claude Opus access | — | ✓ | ✓ | ✓ |
| Shared Projects (team) | — | — | ✓ | ✓ |
| Admin controls & analytics | — | — | ✓ | ✓ |
| SSO / SAML | — | — | — | ✓ |
| Data privacy guarantees | — | — | ✓ | ✓ |
| Custom retention policies | — | — | — | ✓ |
Settings: Do These Before Your First Clinical Session
Most clinicians skip settings entirely and wonder why Claude does not seem to know anything about them. The settings are where you stop being a stranger to your own AI tool. These take under 10 minutes and change every subsequent interaction.
This is Claude's permanent briefing about who you are. It loads before every single conversation — including ones with no other context. Without it, Claude treats you as a generic user.
Write in your profile:
Claude builds a memory of facts about you from your conversations — collaborator names, platform preferences, ongoing projects, recurring rules. You can view every memory entry, correct errors, and delete anything outdated or wrong.
Controls which tools and capabilities are active by default. Most are off until you turn them on — and they stay off even when they would have helped.
Upload a sample of your own writing and Claude calibrates its output to match your voice and register. Most useful for anyone using Claude to produce content — newsletters, manuscripts, patient communications, LinkedIn posts.
Projects
A Project is a persistent workspace inside Claude that carries your instructions, files, and context across every session — indefinitely. Without a Project, Claude starts fresh each time you open a new conversation. With one, it already knows your role, your standards, your files, and your workflow before you type a word.
What a Project contains
A text field where you write your standing rules. Who you are. What you need. How Claude should behave. What it should never do. This loads into every conversation in the Project automatically.
PDFs, Word docs, spreadsheets — any reference material Claude should always have access to. Guidelines, protocols, past work, templates. Upload once; available in every session inside this Project.
All conversations inside a Project are grouped together. You can return to any prior conversation, continue where you left off, or start a new one — the instructions and files are always there.
Named instruction blocks you define inside the Project Instructions. Each has a trigger word. When you type the trigger, Claude executes the behavior you defined for it. See the Skills section below.
How to create a Project
What to put in Project Instructions
Think of Project Instructions as the briefing you give a highly capable colleague before they join your team. Cover these five things:
| Element | What to write | Example |
|---|---|---|
| Your identity | Who you are and what this Project is for | "I am a practicing obstetrician at an academic medical center. This Project supports my monthly journal peer review work." |
| Behavioral rules | How Claude should communicate and at what depth | "Respond at a peer-to-peer clinical level. Use correct medical terminology. Do not explain foundational concepts unless I ask." |
| Output standards | Format, citations, length, structure | "All references in Vancouver format. Flag any unverifiable DOI with ⚠️ UNVERIFIED. Default to prose, not bullet lists." |
| Hard constraints | What Claude must never do in this context | "Do not fabricate citations. Do not add generic medical disclaimers. Do not hedge when evidence is clear." |
| Skills (optional) | Named behavior blocks with trigger words | "When I write 'ReviewStart:', treat the uploaded file as a manuscript and begin a structured peer review using these criteria: [criteria]" |
Skills: Named Behaviors Inside a Project
A Skill is a named instruction block that lives in your Project Instructions and activates when you type its trigger word. It is not a special Claude feature — it is a convention you create. The power is in the consistency: the same task, executed the same way, every time, without re-engineering the context.
To create that Skill, you add this block once to your Project Instructions:
How to Create, Save, and Share a Skill
A Skill is plain text. You write it once, paste it into your Project Instructions, and Claude reads it every session. No special files, no technical setup. Here is exactly how.
Use this exact structure. The trigger word is what you will type in any conversation to activate it.
Claude.ai → Projects → your Project → click the pencil/edit icon on Project Instructions → paste the Skill block at the bottom → save. That is it. Claude reads it at the start of every conversation in that Project.
Open a new conversation inside the Project. Type only the trigger word and see what Claude does. If it does not behave as expected, go back to Step 1 and make the instructions more specific. One iteration is usually enough.
Your Skills live inside Claude's Project Instructions — they are not stored as separate files. To keep a backup or share them:
A Skill is plain text — share it like any text document.
5 Skills Every Clinician Should Build First
These five cover the tasks every clinician repeats most: reading the literature, critiquing guidelines, communicating with patients, teaching, and verifying references. Click "Build This Skill" on any card — Claude will interview you and generate a customized Skill block ready to paste into your Project Instructions.
Your Claude Setup: The Configuration Stack
Most clinicians open Claude and start typing. That is like showing up to a consultation without telling the consultant who you are, what specialty you practice, or what you already know. The configuration stack is how you tell Claude who it is working with — once, permanently, at every level.
Layer by Layer: What to Put Where
Personality and Style: Making Claude Sound Right
Claude's default register is helpful generalist. You can shift it — in Settings, in Project instructions, or at the start of any session — toward the tone and depth your work requires.
Tell Claude the level you want. "Respond at the level of an MFM colleague — full terminology, no explanatory asides, assume I know the basics" produces a completely different output than the default.
For academic writing, give Claude your voice: a paragraph you have written, a paper you have published, a phrase you use habitually. It calibrates to that style faster than any description of it.
Claude defaults to disclaimers, caveats, and hedges. For clinical expert users, these add noise. You can suppress them explicitly — and should, for your Project instructions.
Claude defaults to bullet points and headers. Tell it what you actually want — prose, tables, numbered lists, or specific structures like SOAP or PICO. Set this in User Preferences or Project instructions.
Skills: Giving Claude a Standing Job Description
A Skill is a saved instruction set that pre-loads specific behaviors for a recurring task type. Instead of re-engineering the context every time you need a literature summary or a manuscript review, the Skill does it for you. Think of each Skill as a standing referral to a sub-specialist who already knows your standards.
The Full Configuration Checklist
Run this once when you set up Claude for clinical use. Revisit it whenever your needs change.
Context Engineering: The Skill That Determines Everything
The industry used to call it "prompt engineering." That framing was too narrow. What you are actually doing is engineering the context Claude thinks inside. The model is fixed. The context is yours to build.
The Seven Layers of Clinical Context
A fully engineered clinical context is built from seven layers. Most clinicians provide two or three. The difference in output quality is not marginal — it is categorical.
Before and After: The Same Question, Two Different Worlds
These paired examples show what changes when context is engineered deliberately. The question is identical. The output quality is not.
The SCOPE Framework for Clinical Context
A five-element checklist you can run mentally before any clinical prompt. If you can answer all five in under 30 seconds, your context is ready.
Who am I? What is my role, specialty, and clinical context? Academic MFM vs. community ObGyn vs. resident on call — each implies different depth, different defaults.
The full patient situation: GA, parity, comorbidities, medications, relevant history, current vitals and labs. Not what you think is relevant — all of it. Let Claude decide what matters.
One precise task. "Help me" is not an objective. "Rank differentials by probability with distinguishing features" is an objective. The more specific the task, the more targeted the response.
Constraints and format. Word count, reading level, citation format, what to include and exclude, what to flag. Without parameters, Claude fills in defaults — which may not match your needs.
When style, tone, or structure matters, give one example of what good looks like. A past review, a handout you liked, a paragraph in your voice. One example is worth a hundred adjectives.
The Six Most Common Context Mistakes
| Mistake | What it looks like | The fix |
|---|---|---|
| No role assignment | "What causes elevated liver enzymes in pregnancy?" | Start with: "I am an MFM specialist at an academic center. My patient is..." — Claude calibrates depth, terminology, and assumptions accordingly. |
| Omitting gestational age | "Patient has elevated BP and headache" | GA changes everything in obstetrics. 20 weeks vs. 36 weeks with the same presentation triggers completely different workups and management thresholds. |
| No output format | "Explain the management of preeclampsia" | Specify: "Format as a decision tree / three-column table / bulleted protocol / 200-word summary for a patient." Format shapes what Claude produces as much as the question does. |
| Asking for everything at once | "Tell me everything about shoulder dystocia" | One specific task per prompt. "List the HELPERR maneuvers with the evidence grade for each" produces a usable answer. "Tell me everything" produces a textbook chapter. |
| No citation instruction | Accepting numbered references without specifying format or verification | Always add: "Vancouver format. Flag any PMID or DOI you cannot verify with ⚠️ UNVERIFIED." AI models can and do fabricate plausible-looking citations. |
| Treating uncertainty as failure | Re-prompting when Claude says evidence is limited or conflicting | Ask Claude to explicitly flag uncertainty: "Note where evidence is weak, contested, or expert-opinion only." Uncertainty acknowledgment is a feature, not a bug. |
Ready-to-Use ObGyn Contexts
Copy any context template below. Fill the bracketed fields with your specific clinical situation. Each one is engineered to give Claude the full context it needs to reason at the level of an experienced clinician — not a generic one.
Self-Assessment: AI Workflow Literacy
10 questions. Tests your ability to match task to workflow, use Claude features effectively, and avoid common mistakes. No data leaves your browser.
Quick Reference
Workflow Decision Guide
| Your task | Best mode | Key tip |
|---|---|---|
| Quick DDx or drug question | Focused Session | Include GA, comorbidities, recent labs |
| Reviewing an uploaded guideline PDF | Workspace | Upload the PDF, then ask specific Qs |
| Manuscript editing or co-authoring | Projects | Include citation format + style examples |
| Journal peer review | Projects | Store your criteria + past reviews |
| Resident teaching case | Workspace or Projects | Upload curriculum objectives |
| Patient handout draft | Focused Session | Specify reading level (7th–8th grade) |
| Literature synthesis / grant background | Deep Research | Enable web search; allow 20–30 min |
| Statistical analysis of a dataset | Workspace | Upload CSV/Excel; ask for specific tests |
| Comparing two protocols | Workspace | Upload both docs in same session |
| Building a clinical calculator | Focused Session + Artifacts | Ask for single-file HTML output |
Claude Features at a Glance
| Feature | What it does | When to use | Access |
|---|---|---|---|
| Extended Thinking | Deep step-by-step reasoning | Complex diagnosis, guideline critique | Pro |
| Web Search | Real-time internet access | Recent trials, drug alerts, news | Free + Pro |
| Document Upload | Read PDFs, Word, Excel, images | Guideline review, data analysis | Free + Pro |
| Artifacts | Generates docs/code/tools in preview | Patient handouts, calculators, slides | Free + Pro |
| Projects | Persistent instructions + files | Recurring workflows, research programs | Pro |
| Memory | Remembers you across chats | Style preferences, specialty context | Pro |
| Deep Research | Multi-source research report | Systematic reviews, grant backgrounds | Pro |
| Skills (in Projects) | Saved behavior templates | Recurring task types | Pro |
The 5 Context Engineering Rules